Post-traumatic stress disorder (PTSD) has become an important public health problem. However, the conventional therapeutic strategy, including pharmacotherapy and cognitive behavioral therapy, has limitations. Neurofeedback is a technique that utilizes electroencephalography (EEG) signaling to monitor human physiological functions and is widely used to treat patients with PTSD. The purpose of our study is to assess the efficacy and safety level of neurofeedback treatment in patients with PTSD using quantitative EEG.
Neurofeedback is widely used for various psychiatric diseases, including PTSD. It has an advantage over CBT because it does not re-expose patients with PTSD to the traumatic event. Several studies have reported on the effects of neurofeedback on patients with PTSD. However, most of these studies used a relatively small sample size.11, 58, 59 Additionally, some did not feature a control group and, therefore, could not account for the natural history effect of the disease, regression to mean, and several non-specific effects.15, 16 Some studies did not report the exact location of the electrode.18 Several studies did not report the neurofeedback protocol, which limits their reproducibility and the clinical utility of their results.17, 26