This conclusion has serious ethical and legal implications. Could a psychopath mount a legal defense by saying “my brain made me do it”? Or my “genes made me do it”? Is this any different from saying my rotten childhood made me do it? Psychopaths know right from wrong – they just don’t care. That is what society calls “bad”, not “mad”. But if they are constitutionally incapable of caring, can they really be blamed for it? On the other hand, if violent psychopaths are a continuing danger to society and completely refractory to rehabilitation, what is to be done with them? Perhaps, as has been proposed in the UK, people with the extreme psychopathic personality profile (or maybe in the near future even a specific genetic profile?) should be monitored or segregated even before they commit a crime.